{"id":2156,"date":"2024-08-27T09:32:23","date_gmt":"2024-08-27T06:02:23","guid":{"rendered":"https:\/\/tebnology-co.com\/cancer-stem-cell-related-gene-expression-as-a-potential-biomarker-for-first-line-onc201-imi-jumping-response-in-solid-tumors\/"},"modified":"2024-09-11T16:15:44","modified_gmt":"2024-09-11T12:45:44","slug":"cancer-stem-cell-related-gene-expression-as-a-potential-biomarker-for-first-line-onc201-imi-jumping-response-in-solid-tumors","status":"publish","type":"post","link":"https:\/\/tebnology-co.com\/en\/cancer-stem-cell-related-gene-expression-as-a-potential-biomarker-for-first-line-onc201-imi-jumping-response-in-solid-tumors\/","title":{"rendered":"Cancer stem cell-related gene expression as a potential biomarker for first-line ONC201 Imi-jumping response in solid tumors."},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Cancer stem cells (CSCs) Promising results from clinical trials of CSC inhibitors have confirmed CSCs as therapeutic targets. ONC201 is a first-in-class anticancer small molecule in phase I\/II clinical trials for advanced cancer. We have previously shown that ONC201 targets the self-renewal of chemotherapy-resistant colorectal CSCs by inhibiting Akt\/ERK and inducing DR5\/TRIL.   <\/p>\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p> (CSCs) Promising results from clinical trials of CSC inhibitors have confirmed CSCs as therapeutic targets.<\/p>\n","protected":false},"author":1,"featured_media":1815,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[54],"tags":[],"class_list":["post-2156","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-article-en"],"_links":{"self":[{"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/posts\/2156","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/comments?post=2156"}],"version-history":[{"count":1,"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/posts\/2156\/revisions"}],"predecessor-version":[{"id":2157,"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/posts\/2156\/revisions\/2157"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/media\/1815"}],"wp:attachment":[{"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/media?parent=2156"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/categories?post=2156"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tebnology-co.com\/en\/wp-json\/wp\/v2\/tags?post=2156"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}